Invitrogen™ H3K9acS10ph Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA125462

Catalog No. PIPA125462

Description

Recommended positive controls: NIH3T3 treated with sodium butyrate. PA1-25462 is expected to cross react with mouse, rat, Xenopus laevis, bovine, C. elegans, chicken, Drosophilia melanogaster, and a wide range of other species due to sequence homology Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: H3K9acS10ph
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H3C15
• Gene Alias: Acetyl H3; Acetyl Histone H3; B0035.7; CELE_T10C6.12; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; h3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K9; H3 K9ac; H3 S10; H3 S10ph; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3 histone A; H3.3 histone B; H3.3A; H3.3b; H3.5; H3.5 histone; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3A protein; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K9; H3K9ac; H3K9acS10p; H3Lys9acSer10p; H3Lys9acSer10ph; h3r; H3s10; H3S10ph; his-12; his-16; his-19; his-21; His3; his-3; His3:CG31613; His3:CG31613-PA; His3:CG33803; His3:CG33806; His3:CG33809; His3:CG33812; His3:CG33815; His3:CG33818; His3:CG33821; His3:CG33824; His3:CG33827; His3:CG33830; His3:CG33833; His3:CG33836; His3:CG33839; His3:CG33842; His3:CG33845; His3:CG33848; His3:CG33851; His3:CG33854; His3:CG33857; His3:CG33860; His3:CG33863; His3:CG33866; his-30; his-33; his-43; his-47; his-51; his-53; his-57; his-61; his-65; his-68; his-7; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; HIST1H3F; Hist1h3g; hist1h3g.L; Hist1h3h; HIST1H3I; HIST1H3J; hist2h3; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3g protein L homeolog; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; Histone H2A; Histone H3; Histone H3 K9; Histone H3 K9ac; Histone H3 S10; Histone H3 S10ph; histone H3.1; Histone H3.2; histone H3.3; Histone H3.3C; histone H3.3C-like; Histone H3.5; histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; histone H3/l; Histone H3/m; histone H3/o; Histone H3K9; Histone H3K9ac; Histone H3K9acS10ph; histone H3-like; Histone H3S10; Histone H3S10ph; histone variant H3.5; K06C4.11; K06C4.3; M32461; phospho Histone 3; phospho Histone H3; Phospho-Acetyl-H3 S10 K9; Phospho-Acetyl-H3 Ser10 Lys9; Phospho-Acetyl-Histone H3 S10 K9; Phospho-Acetyl-Histone H3 Ser10 Lys9; PP781; similar to H3 histone, family 3A; T10C6.12; T23D8.6; Unknown (protein for MGC:128166); XELAEV_18028537mg; ZK131.10; ZK131.6
• Host Species: Rabbit
• Purification Method: IgG Fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 107131750, 126961, 180073, 260423, 318847, 319150, 319152, 333932, 360198, 399088, 616800, 788250, 8350, 8356, 8357, 8358, 8968, 97114
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 3.7 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P09588, P68431, P68433, P84228, Q71DI3
• Gene Symbols: H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, h3c8.S, his-3, His3:CG31613, LOC107131750
• Immunogen: Synthetic, acetylated and phosphorylated (acetyl K9 & phospho S10) peptide, conjugated to KLH, corresponding to the N-terminal residues 7-20 of human Histone H3.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Chicken, Amphibian, Drosophila, Frog, C. elegans
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov