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Phospho-Acinus (Ser1180) Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5105962
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PIPA5105962 100 μL
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Catalog No. PIPA5105962 Supplier Thermo Scientific Supplier No. PA5105962

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.

ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Acinus (Ser1180)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ACIN1
Gene Accession No. Q9JIX8, Q9UKV3
Gene Alias 2610036I19Rik; 2610510L13Rik; Acin1; ACINUS; acinusL; acinusS; Acn; apoptotic chromatin condensation inducer 1; apoptotic chromatin condensation inducer in the nucleus; C79325; DKFZp667N107; fSAP152; functional spliceosome-associated protein 152; KIAA0670; mKIAA0670
Gene Symbols ACIN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACIN1(Accession Q9UKV3), corresponding to amino acid residues around phosphorylated Ser1180.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22985, 305884, 56215
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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