Phospho-AKT1/2/3 (Ser473) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0557	100 μL

Catalog No. 50-198-0557 Supplier Bioss Supplier No. BS0876R

Description

Rabbit Polyclonal Antibody

AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.

Specifications

• Antigen: Phospho-AKT1/2/3 (Ser473)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Akt2
• Gene Accession No.: P31749, P31751, Q9Y243
• Gene Alias: 2410016A19Rik; AI851531; Akt; Akt kinase; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT serine/threonine kinase 3; AKT/PKB; Akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; AKT2; AKT2 kinase; Akt3; AKT3 kinase; akt3a; AW554154; cb945; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; D930002M15Rik; DAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; dAkt1; DAKT1/PKB; DKFZp434N0250; Dmel\CG4006; Dmel_CG4006; Dpkb; DRAC-PK; DRAC-PK66; DRAC-PK85; HIHGHH; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; MPPH; MPPH2; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 1; murine thymoma viral (v-akt) oncogene homolog 2; Nmf350; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/Akt; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBB; PKBbeta; PKBG; PKB-GAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B alpha; Protein kinase B beta; Protein kinase B gamma; protein kinase B, beta; protein kinase B, gamma; protein kinase B-alpha; Proto-oncogene c-Akt; putative v-akt murine thymoma viral oncoprotein 2; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; serine-threonine protein kinase; si:ch211-221n23.2; STK-2; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; thymoma viral proto-oncogene 2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 1; v-akt murine thymoma viral oncogene-like 3; v-akt murine thymoma viral oncogene-like protein 1
• Gene Symbols: AKT1, Akt2, Akt3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Ser473.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10000, 207, 208
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG