Invitrogen™ Phospho-AKT2 (Ser474) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121255

Catalog No. PIPA5121255

Description

Positive test controls include: 293. The target is usually found in the following locations: Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein. Immunogen sequence: QFSYS.

AKT2 is a phosphoinositide-dependent serine/threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone. Akt is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.

Specifications

• Antigen: Phospho-AKT2 (Ser474)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Akt2
• Gene Alias: 2410016A19Rik; AKT serine/threonine kinase 2; Akt2; AKT2 kinase; AW554154; HIHGHH; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB; PKB beta; PKBB; PKBBETA; PRKBB; protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11652, 208, 25233
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P31751, P47197, Q60823
• Gene Symbols: Akt2
• Immunogen: A synthetic phosphorylated peptide around S474 of human AKT2 (NP_001617.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG