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Invitrogen™ Phospho-ALOX5 (Ser272) Polyclonal Antibody
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Catalog No. PIPA5105142
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PIPA5105142 100 μL
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Catalog No. PIPA5105142 Supplier Invitrogen™ Supplier No. PA5105142
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of 5 Lipoxygenase only when phosphorylated at Ser272.

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ALOX5 (Ser272)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ALOX5
Gene Accession No. P09917, P12527, P48999
Gene Alias 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
Gene Symbols ALOX5
Host Species Rabbit
Immunogen A synthesized peptide derived from human ALOX5(Accession P09917), corresponding to amino acid residues around phosphorylated Ser272.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11689, 240, 25290
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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