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Phospho-alpha Adducin (Ser436) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983935
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50-198-3935 100 μL
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Catalog No. 50-198-3935 Supplier Bioss Supplier No. BS15968R
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Description

Rabbit Polyclonal Antibody

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Specifications

Antigen Phospho-alpha Adducin (Ser436)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ADD1
Gene Accession No. P35611
Gene Alias ADD1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; Alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha
Gene Symbols ADD1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 118
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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