Phospho-alpha Adducin (Ser436) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS15968R

Catalog No. 50-198-3935

Description

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Specifications

• Antigen: Phospho-alpha Adducin (Ser436)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADD1
• Gene Alias: ADD1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; Alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 118
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P35611
• Gene Symbols: ADD1
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG