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Invitrogen™ Phospho-ANKRD28 (Ser1040) Polyclonal Antibody
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Catalog No. PIPA564647
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PIPA564647 100 μL
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Catalog No. PIPA564647 Supplier Invitrogen™ Supplier No. PA564647
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Description

Rabbit Polyclonal Antibody

Phospho-ANKRD28 (Ser1040) Polyclonal Antibody detects endogenous levels of ANKRD28 only when phosphorylated at Ser1040.

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ANKRD28 (Ser1040)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ANKRD28
Gene Accession No. O15084, Q505D1
Gene Alias AI465466; AI604979; ANKRD28; ankyrin repeat domain 28; ankyrin repeat domain-containing protein 28; E430019N21Rik; KIAA0379; mKIAA0379; phosphatase interactor targeting K protein; phosphatase interactor targeting protein hnRNP K; PITK; PP6-ARS-A; PPP1R65; protein phosphatase 1, regulatory subunit 65; protein phosphatase 6 ankyrin repeat subunit A; RGD1559931; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; serine/threonine-protein phosphatase 6 regulatory subunit ARS-A
Gene Symbols ANKRD28
Host Species Rabbit
Immunogen A synthesized peptide derived from human ANKRD28 (Phospho-Ser1040).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 105522, 23243
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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