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Phospho-APBB1 (Ser347) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986381
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50-198-6381 100 μL
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Catalog No. 50-198-6381 Supplier Bioss Supplier No. BS5166R
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Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer′s disease amyloid precursor protein , transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product′s nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer′s disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.

Specifications

Antigen Phospho-APBB1 (Ser347)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene APBB1
Gene Accession No. O00213
Gene Alias adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; Apbb1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Gene Symbols APBB1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human APBB1 around the phosphorylation site of Ser347 [SL (p-S)PE].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 322
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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