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Invitrogen™ Phospho-ARHGAP42 (Tyr376) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5105369
Description
Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
Specifications
Phospho-ARHGAP42 (Tyr376) | |
Polyclonal | |
Unconjugated | |
ARHGAP42 | |
9030420J04Rik; Arhgap42; BE136619; Graf3; RGD1564081; Rho GTPase activating protein 42; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; rho-type GTPase-activating protein 42; TMEM133; VRho GTPase activating protein 42 | |
Rabbit | |
Sequential Chromatography | |
RUO | |
143872, 71544 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
A6NI28, B2RQE8 | |
ARHGAP42 | |
A synthesized peptide derived from human ARHGAP42(Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr376. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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