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Invitrogen™ Phospho-ARHGAP42 (Tyr376) Polyclonal Antibody
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Catalog No. PIPA5105369
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PIPA5105369 100 μL
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Catalog No. PIPA5105369 Supplier Invitrogen™ Supplier No. PA5105369
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.

This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ARHGAP42 (Tyr376)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ARHGAP42
Gene Accession No. A6NI28, B2RQE8
Gene Alias 9030420J04Rik; Arhgap42; BE136619; Graf3; RGD1564081; Rho GTPase activating protein 42; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; rho-type GTPase-activating protein 42; TMEM133; VRho GTPase activating protein 42
Gene Symbols ARHGAP42
Host Species Rabbit
Immunogen A synthesized peptide derived from human ARHGAP42(Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr376.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 143872, 71544
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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