Invitrogen™ Phospho-AS160 (Thr642) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597400

Catalog No. PIPA597400

Description

Immunogen sequence: AHTFS; Positive Samples: 293T; Cellular Location: Cytoplasm.

AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).

Specifications

• Antigen: Phospho-AS160 (Thr642)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBC1D4
• Gene Alias: 5930406J04Rik; A930035N22; Akt substrate of 160 kDa; AS160; AV295684; DKFZp779C0666; Kiaa0603; NIDDM5; OTTHUMP00000040818; RGD1561609; RP11-159J2.1; RP11-159J2.3; similar to TBC1 domain family member 4; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC Tre-2; TBC1 domain family member 4; TBC1 domain family, member 4; TBC1D4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 210789, 9882
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O60343, Q8BYJ6
• Gene Symbols: TBC1D4
• Immunogen: A synthetic phosphorylated peptide around T642 of human TBC1D4 (NP_0556472).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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