Invitrogen™ Phospho-AS160 (Thr642) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 441071G

Catalog No. 44-107-1G

Description

Phospho-AS160 (Thr642) Polyclonal Antibody for Western Blot

AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).

Specifications

• Antigen: Phospho-AS160 (Thr642)
• Classification: Polyclonal
• Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
• Gene Accession No.: O60343, Q8BYJ6
• Gene Symbols: TBC1D4
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human AS160 that contains threonine 642. The sequence is conserved in mouse.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: TBC1D4
• Gene Alias: 5930406J04Rik; A930035N22; Akt substrate of 160 kDa; AS160; AV295684; DKFZp779C0666; Kiaa0603; NIDDM5; OTTHUMP00000040818; RGD1561609; RP11-159J2.1; RP11-159J2.3; similar to TBC1 domain family member 4; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC Tre-2; TBC1 domain family member 4; TBC1 domain family, member 4; TBC1D4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 210789, 9882
• Content And Storage: -20°C
• Form: Liquid