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Invitrogen™ Phospho-ATF2 (Thr71) Recombinant Rabbit Monoclonal Antibody (10L9M2)
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Catalog No. PIMA538233
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100 μL
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PIMA538233 100 μL
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Catalog No. PIMA538233 Supplier Invitrogen™ Supplier No. MA538233
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: NIH/3T3 Immunogen sequence: TPTPT.

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ATF2 (Thr71)
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 10L9M2
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Atf2
Gene Accession No. P16951
Gene Alias Activating 2; Activating transcription factor 2; activating transcription factor 2 splice variant ATF2-var2; ATF2; Atf-2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; CREB2; CREB-2; CRE-BP; CREBP1; CRE-BP1; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; D130078H02Rik; D18875; HB16; Histone acetyltransferase ATF2; MGC111558; mXBP; MXBP protein; OTTHUMP00000205345; OTTHUMP00000205347; OTTHUMP00000205348; OTTHUMP00000205350; OTTHUMP00000205352; OTTHUMP00000205353; OTTHUMP00000205354; Tg(Gzma-Klra1)7Wum; TREB7
Gene Symbols Atf2
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around T71 of human ATF2 (P15336).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11909
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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