Phospho-ATF2 (Thr71) Recombinant Rabbit Monoclonal Antibody (ATF2T71-G3), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA537247	Invitrogen™ MA537247	10 Tests
PIMA536946	Invitrogen™ MA536946	100 Tests

Description

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.

Specifications

• Antigen: Phospho-ATF2 (Thr71)
• Applications: Flow Cytometry
• Conjugate: PE
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P15336, P16951
• Gene ID (Entrez): 11909, 1386
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Thr71 of human phospho ATF2.
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Gene: Atf2

• Clone: ATF2T71-G3
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: Activating 2; Activating transcription factor 2; activating transcription factor 2 splice variant ATF2-var2; ATF2; Atf-2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; CREB2; CREB-2; CRE-BP; CREBP1; CRE-BP1; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; D130078H02Rik; D18875; HB16; Histone acetyltransferase ATF2; MGC111558; mXBP; MXBP protein; OTTHUMP00000205345; OTTHUMP00000205347; OTTHUMP00000205348; OTTHUMP00000205350; OTTHUMP00000205352; OTTHUMP00000205353; OTTHUMP00000205354; Tg(Gzma-Klra1)7Wum; TREB7
• Gene Symbols: Atf2
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody