Phospho-ATP citrate lyase (Ser455) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5102	100 μL

Catalog No. 50-198-5102 Supplier Bioss Supplier No. BS3037R

Description

Rabbit Polyclonal Antibody

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: Phospho-ATP citrate lyase (Ser455)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Acly
• Gene Accession No.: P53396
• Gene Alias: A730098H14Rik; ACL; Acly; ATP citrate lyase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPCL; AW538652; Citrate cleavage enzyme; CLATP
• Gene Symbols: Acly
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human ATP citrate lyase around the phosphorylation site of Ser455.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 47
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG