Learn More
Invitrogen™ Phospho-ATR (Ser428) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 720107
Description
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Cat, Sheep and Bovine.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Specifications
Phospho-ATR (Ser428) | |
Polyclonal | |
Unconjugated | |
ATR | |
2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
545 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.5 mg/mL | |
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2 | |
Q13535 | |
ATR | |
Peptide corresponding to Human ATR (aa 424-432). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.