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Invitrogen™ Phospho-ATR (Ser428) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 720107

Catalog No. 72-010-7


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Description

Description

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Cat, Sheep and Bovine.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-ATR (Ser428)
Polyclonal
Unconjugated
ATR
2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
Rabbit
Affinity Chromatography
RUO
545
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.5 mg/mL
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Q13535
ATR
Peptide corresponding to Human ATR (aa 424-432).
100 μg
Primary
Human
Antibody
IgG
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