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Phospho-B-Raf (Thr401) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986418
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50-198-6418 100 μL
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Catalog No. 50-198-6418 Supplier Bioss Supplier No. BS5224R
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Description

Rabbit Polyclonal Antibody

B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Specifications

Antigen Phospho-B-Raf (Thr401)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BRAF
Gene Accession No. P15056
Gene Alias 94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; BRAF; B-raf; B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; Proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; Serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1
Gene Symbols BRAF
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Thr401.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 673
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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