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Invitrogen™ Phospho-Bcl-3 (Ser402) Polyclonal Antibody
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Catalog No. PIPA5118771
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100 μL
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PIPA5118771 100 μL
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Catalog No. PIPA5118771 Supplier Invitrogen™ Supplier No. PA5118771
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of BCL-3 only when phosphorylated at Ser402.

B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
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Specifications

Antigen Phospho-Bcl-3 (Ser402)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Bcl3
Gene Accession No. P20749
Gene Alias AI528691; B cell leukemia/lymphoma 3; B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3 protein homolog; B-cell lymphoma 3-encoded protein; BCL3; BCL-3; Bcl-3 protein; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3
Gene Symbols Bcl3
Host Species Rabbit
Immunogen A synthesized peptide derived from human BCL3(Accession P20749), corresponding to amino acid residues around phosphorylated Ser402.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 602
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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