Phospho-Bcl-xL/BCL2L1 (Thr47) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2356	100 μL

Catalog No. 50-198-2356 Supplier Bioss Supplier No. BS12579R

Description

Rabbit Polyclonal Antibody

The protein encoded the BCL-X gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.

Specifications

• Antigen: Phospho-Bcl-xL/BCL2L1 (Thr47)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: BCL2L1
• Gene Accession No.: Q07817
• Gene Alias: anti-apoptosis regulatory protein; anti-apoptotic Bcl-2 gene family member; anti-apoptotic Bcl-xL; Apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl 2 like 1; Bcl xL; BCL XL/S; Bcl(X)L; bcl-2 L1; BCL2 like 1; BCL2L; Bcl2l1; Bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCL2-like protein 1; Bclx; Bcl-X; Bcl-x long protein; BclxL; bcl-xl; BCL-XL/S; BclXS; bcl-xS; Blc2l; DKFZp781P2092; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
• Gene Symbols: BCL2L1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr47.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 598
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG