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Invitrogen™ Phospho-Beclin 1 (Ser295) Polyclonal Antibody
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Catalog No. PIPA535394
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100 μL
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PIPA535394 100 μL
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Catalog No. PIPA535394 Supplier Invitrogen™ Supplier No. PA535394
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, canine, chicken, mouse, non-human primate, sheep, Xenopus and zebrafish based on 100% sequence homology. In Western blot, additional bands may be observed when using non-immunoprecipitated lysates.

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Beclin 1 (Ser295)
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene BECN1
Gene Accession No. O88597, Q14457, Q91XJ1
Gene Alias 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Gene Symbols BECN1
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser295 of human BECN1 conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114558, 56208, 8678
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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