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Invitrogen™ Phospho-Beclin 1 (Ser90) Polyclonal Antibody
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Catalog No. PIPA5121359
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100 μL
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PIPA5121359 100 μL
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Catalog No. PIPA5121359 Supplier Invitrogen™ Supplier No. PA5121359
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, NIH/3T3. The target is usually found in the following locations: Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endosome, Endosome membrane, Golgi apparatus, Mitochondrion, Mitochondrion membrane, Nucleus, Peripheral membrane protein, autophagosome, trans-Golgi network membrane. Immunogen sequence: MMSTE.

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Beclin 1 (Ser90)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.83 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene BECN1
Gene Accession No. Q14457
Gene Alias 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Gene Symbols BECN1
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8678
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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