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Phospho-BLNK (Tyr84) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989262
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50-198-9262 100 μL
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Catalog No. 50-198-9262 Supplier Bioss Supplier No. BS9687R
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Rabbit Polyclonal Antibody

B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.

Specifications

Antigen Phospho-BLNK (Tyr84)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BLNK
Gene Accession No. Q8WV28
Gene Alias AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; BLNK; BLNK-S; Cytoplasmic adapter protein; Ly57; Ly-57; Lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; SLP-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Gene Symbols BLNK
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr84 [EM (p-Y)VM].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29760
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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