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Invitrogen™ Phospho-BLNK (Tyr84) Recombinant Rabbit Monoclonal Antibody (BLNKY84-H4)
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Catalog No. PIMA537084
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200 μL
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PIMA537084 20 μL
PIMA528004 200 μL
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Catalog No. PIMA537084 Supplier Invitrogen™ Supplier No. MA537084
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
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Specifications

Antigen Phospho-BLNK (Tyr84)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone BLNKY84-H4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.1% BSA and 0.02% sodium azide; pH 7.4
Gene BLNK
Gene Accession No. Q8WV28
Gene Alias AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Gene Symbols BLNK
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29760
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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WARNING: Cancer - www.P65Warnings.ca.gov
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