Invitrogen™ Phospho-BRK (Tyr342) Polyclonal Antibody

Catalog No.	Quantity
PIPA5105867	100 μL

Catalog No. PIPA5105867 Supplier Invitrogen™ Supplier No. PA5105867

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of BRK only when phosphorylated at Tyr342.

Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.

Specifications

• Antigen: Phospho-BRK (Tyr342)
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: PTK6
• Gene Accession No.: Q13882, Q64434
• Gene Alias: ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
• Gene Symbols: PTK6
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human PTK6(Accession Q13882), corresponding to amino acid residues around phosphorylated Tyr342.
• Purification Method: sequential chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20459, 366275, 5753
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG