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Invitrogen™ Phospho-c-Jun (Tyr170) Polyclonal Antibody
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Catalog No. PIPA5104751
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100 μL
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PIPA5104751 100 μL
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Catalog No. PIPA5104751 Supplier Invitrogen™ Supplier No. PA5104751
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of c-Jun only when phosphorylated at Tyrosine 170.

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-c-Jun (Tyr170)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene JUN
Gene Accession No. P05412, P05627, P17325
Gene Alias Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Gene Symbols JUN
Host Species Rabbit
Immunogen A synthesized peptide derived from human JUN(Accession P05412), corresponding to amino acid residues around phosphorylated Tyr170.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16476, 24516, 3725
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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