Phospho-c-Jun (Tyr170) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS5463R

Catalog No. 50-198-6583

Description

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.

Specifications

• Antigen: Phospho-c-Jun (Tyr170)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JUN
• Gene Alias: Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; c-jun; C-JUN protein; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; Jun; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; Proto-oncogene c-Jun; Rjg-9; Transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3725
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P05412
• Gene Symbols: JUN
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Tyr170.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG