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Phospho-C-Myb (Thr486) Polyclonal Antibody, Rockland™
SDP

Catalog No. 501992013
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100 μg
25 μL
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50-199-2013 100 μg
50-199-2014 25 μL
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Catalog No. 50-199-2013 Supplier Rockland Immunochemicals Supplier No. 600401C47
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity-purified antibody is directed against the phosphorylated form of mouse c-Myb protein at the pT486 residue. Reactivity occurs against mouse c-Myb pT486 protein and the antibody is specific for the phosphorylated form of the protein.This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells. Reactivity with non-phosphorylated mouse c-Myb is minimal by ELISA and western blot. A BLAST analysis was used to suggest reactivity with c-Myb from mouse based on a 100% homology with the immunizing sequence. Expect reactivity with c-Myb from rat, pig, human, horse, platypus, opossum, orangutan, spider monkey, bonobo, gorilla, and chimpanzee; with a v-myb myeloblastosis viral oncogene homolog, all isoforms (also avian version) from human; and with a protooncogene c-myb, and a v-myb myeloblastosis viral oncogene homolog (avian), both from cattle, all based on a 93% homology with the immunizing sequence. Cross-reactivity with c-Myb from other sources has not been determined.

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Specifications

Antigen Phospho-C-Myb (Thr486)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.91 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene MYB
Gene Accession No. P06876
Gene Alias AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; Myb; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; myeloblastosis oncogene; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Gene Symbols MYB
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17863
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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