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Invitrogen™ Phospho-Caldesmon (Ser759) Polyclonal Antibody
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Catalog No. PIPA5105975
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PIPA5105975 100 μL
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Catalog No. PIPA5105975 Supplier Invitrogen™ Supplier No. PA5105975
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Caldesmon only when phosphorylated at Ser759.

Caldesmon is a developmentally regulated protein involved in smooth muscle and non muscle contraction. Two closely related variants of human caldesmon have been identified which differ in their electrophorectic mobility and cellular distribution. The h caldesmon variant (120 - 150 kDa) is predominantly expressed in smooth muscle whereas l caldesmon (70 - 80 kDa) is found in non-muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle.
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Specifications

Antigen Phospho-Caldesmon (Ser759)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cald1
Gene Accession No. Q05682, Q62736
Gene Alias 4833423D12Rik; AI195384; AV071549; AW536160; C920027I18Rik; CAD; Cald1; Caldesmon; caldesmon 1; CDM; HCAD; H-CAD; h-caldesmon; LCAD; L-CAD; L-caldesmon; MGC21352; NAG22; Non-muscle caldesmon; OTTHUMP00000207950; OTTHUMP00000207953; OTTHUMP00000207954; OTTHUMP00000207955; OTTHUMP00000214473; smooth muscle caldesmon; testis secretory sperm-binding protein Li 227n
Gene Symbols Cald1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CALD1(Accession Q05682), corresponding to amino acid residues around phosphorylated Ser759.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109624, 25687, 800
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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