Phospho-Caspase 2 (Ser157) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538566

Catalog No. PIPA538566

Description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: Phospho-Caspase 2 (Ser157)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASP2
• Gene Alias: CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57, caspase-2, neural precursor cell expressed developmentally down-regulated protein 2, protease ICH-1, protein phosphatase 1, regulatory subunit 57
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 835
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P42575
• Gene Symbols: CASP2
• Immunogen: A synthetic phosphopeptide derived from human Caspase 2 around the phosphorylation site of Ser157 (R-L-SP-T-D)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG