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Phospho-Caveolin-1 (Tyr14) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985437
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50-198-5437 100 μL
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Catalog No. 50-198-5437 Supplier Bioss Supplier No. BS3480R
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Rabbit Polyclonal Antibody

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Specifications

Antigen Phospho-Caveolin-1 (Tyr14)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CAV1
Gene Accession No. Q03135
Gene Alias BOS_4208; BSCL3; Cav; CAV1; Cav-1; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; Caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; variant a; variant b; Vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Gene Symbols CAV1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human Caveolin-1 around the phosphorylation site of Tyr14 [HL (p-Y)TV].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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