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Invitrogen™ Phospho-Caveolin 2 (Tyr19) Polyclonal Antibody, Alexa Fluor™ 488
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Catalog No. PIPA1060A48
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50 μg
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PIPA1060A48 50 μg
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Catalog No. PIPA1060A48 Supplier Invitrogen™ Supplier No. PA1060A488
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Rabbit Polyclonal Antibody

PA1-060 detects phospho-caveolin-2 Y19 from human and mouse samples. Immunofluorescent staining of phospho-caveolin-2 Y19 in NIH 3T3 cells using PA1-060-A488 results in a distinct punctate staining pattern at the cell periphery.

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
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Specifications

Antigen Phospho-Caveolin 2 (Tyr19)
Applications Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene CAV2
Gene Accession No. P51636, Q9WVC3
Gene Alias AI447843; CAV; CAV2; caveolae; caveolae protein, 20-kD; caveolin 2; caveolin 2 isoform a and b; caveolin-2; MGC12294; Phospho-CAV2
Gene Symbols CAV2
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues M(14) A D D A (pY) S H H S G C(25) of mouse CAV2.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12390, 858
Target Species Human, Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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