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Invitrogen™ Phospho-CD104 (Thr1487) Polyclonal Antibody
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Catalog No. PIPA5114588
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100 μL
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Catalog No. Quantity
PIPA5114588 100 μL
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Catalog No. PIPA5114588 Supplier Invitrogen™ Supplier No. PA5114588
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Integrin beta 4 only when phosphorylated at Thr1487.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CD104 (Thr1487)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene ITGB4
Gene Accession No. A2A863, P16144, Q64632
Gene Alias AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4
Gene Symbols ITGB4
Host Species Rabbit
Immunogen A synthesized peptide derived from human Integrin beta 4 around the phosphorylation site of Thr1487.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192897, 25724, 3691
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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