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Invitrogen™ Phospho-Cdc25B (Ser353) Polyclonal Antibody
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Catalog No. PIPA5104865
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PIPA5104865 100 μL
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Catalog No. PIPA5104865 Supplier Invitrogen™ Supplier No. PA5104865
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CDC25B only when phosphorylated at Serine 353.

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Cdc25B (Ser353)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDC25B
Gene Accession No. P30305, P30306
Gene Alias AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Gene Symbols CDC25B
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDC25B(Accession P30305), corresponding to amino acid residues around phosphorylated Ser353.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12531, 994
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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