Invitrogen™ Phospho-Cdc25B (Ser353) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104865

Catalog No. PIPA5104865

Description

Antibody detects endogenous levels of CDC25B only when phosphorylated at Serine 353.

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Specifications

• Antigen: Phospho-Cdc25B (Ser353)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC25B
• Gene Alias: AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12531, 994
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P30305, P30306
• Gene Symbols: CDC25B
• Immunogen: A synthesized peptide derived from human CDC25B(Accession P30305), corresponding to amino acid residues around phosphorylated Ser353.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov