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Invitrogen™ Cdc6 Polyclonal Antibody
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Catalog No. PIPA5102925
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100 μL
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PIPA5102925 100 μL
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Catalog No. PIPA5102925 Supplier Invitrogen™ Supplier No. PA5102925
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CDC6.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDC6
Gene Accession No. O89033, Q99741
Gene Alias CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
Gene Symbols CDC6
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDC6(Accession Q99741), corresponding to amino acid residues L34-G84.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23834, 990
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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