Invitrogen™ Phospho-Cdc6 (Ser54) Recombinant Rabbit Monoclonal Antibody (0K9Y2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538237

Catalog No. PIMA538237

Description

Positive Samples: NIH/3T3 Immunogen sequence: PLSPR.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specifications

• Antigen: Phospho-Cdc6 (Ser54)
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O89033
• Gene Symbols: CDC6
• Immunogen: A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 0K9Y2
• Conjugate: Unconjugated
• Gene: CDC6
• Gene Alias: CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23834
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid