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Invitrogen™ Phospho-Cdc6 (Ser54) Recombinant Rabbit Monoclonal Antibody (0K9Y2)
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Catalog No. PIMA538237
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100 μL
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PIMA538237 100 μL
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Catalog No. PIMA538237 Supplier Invitrogen™ Supplier No. MA538237
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: NIH/3T3 Immunogen sequence: PLSPR.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Cdc6 (Ser54)
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 0K9Y2
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CDC6
Gene Accession No. O89033
Gene Alias CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
Gene Symbols CDC6
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23834
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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