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Phospho-CDK2 (Thr14) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986457
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50-198-6457 100 μL
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Catalog No. 50-198-6457 Supplier Bioss Supplier No. BS5277R
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Description

Rabbit Polyclonal Antibody

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Specifications

Antigen Phospho-CDK2 (Thr14)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CDK2
Gene Accession No. P24941
Gene Alias A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; Cdkn2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Gene Symbols CDK2
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human CDK2 around the phosphorylation site of Thr14 [EG (p-T)YG].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1017
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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