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Invitrogen™ Phospho-CDK2 (Thr160) Polyclonal Antibody
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Catalog No. PIPA5104849
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Quantity:
100 μL
Catalog No. Quantity
PIPA5104849 100 μL
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Catalog No. PIPA5104849

Supplier: Invitrogen™ PA5104849

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CDK2 only when phosphorylated at Threonine 160.

CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CDK2 (Thr160)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDK2
Gene Accession No. P24941, P97377, Q63699
Gene Alias A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Gene Symbols CDK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDK2(Accession P24941), corresponding to amino acid residues around phosphorylated Thr160.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1017, 12566, 362817
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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