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Invitrogen™ Phospho-CDK5 (Tyr15) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA577909
Description
Positive Control: HeLa Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
Specifications
Phospho-CDK5 (Tyr15) | |
Polyclonal | |
Unconjugated | |
CDK5 | |
AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
1020, 12568, 140908 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
P49615, Q00535, Q03114 | |
CDK5 | |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Human CDK5 (phospho Tyr15). The exact sequence is proprietary. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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