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Invitrogen™ Phospho-cGKII (Ser126) Polyclonal Antibody
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Catalog No. PIPA5105913
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PIPA5105913 100 μL
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Catalog No. PIPA5105913 Supplier Invitrogen™ Supplier No. PA5105913
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CGK2 only when phosphorylated at Ser126.

PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-cGKII (Ser126)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PRKG2
Gene Accession No. Q13237, Q61410, Q64595
Gene Alias AW212535; cGK 2; cGK2; cGKII; cGK-II; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; GDPKII; PRKG2; PRKGR2; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; testicular tissue protein Li 99; type II cGMP-dependent protein kinase
Gene Symbols PRKG2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PRKG2(Accession Q13237), corresponding to amino acid residues around phosphorylated Ser126.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19092, 25523, 5593
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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