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Invitrogen™ Phospho-Claudin 5 (Tyr217) Polyclonal Antibody
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Catalog No. PIPA537756
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100 μL
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PIPA537756 100 μL
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Catalog No. PIPA537756 Supplier Invitrogen™ Supplier No. PA537756
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Description

Rabbit Polyclonal Antibody

A suggested positive control for IHC is human brain tissue.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Claudin 5 (Tyr217)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CLDN5
Gene Accession No. O00501, O54942, Q9JKD6
Gene Alias AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Gene Symbols CLDN5
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12741, 65131, 7122
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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