Phospho-Claudin 6 (Tyr219) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5618	100 μL

Catalog No. 50-198-5618 Supplier Bioss Supplier No. BS3736R

Description

Rabbit Polyclonal Antibody

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Specifications

• Antigen: Phospho-Claudin 6 (Tyr219)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: CLDN6
• Gene Accession No.: P56747
• Gene Alias: AL024037; claudin 6; Claudin6; Claudin-6; CLD6; Cldn6; Skullin; tight junction molecule claudin 6; UNQ757/PRO1488
• Gene Symbols: CLDN6
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Claudin 6 around the phosphorylation site of Tyr219.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9074
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG