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Phospho-Cofilin (Tyr140) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986445
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50-198-6445 100 μL
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Catalog No. 50-198-6445 Supplier Bioss Supplier No. BS5258R
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Description

Rabbit Polyclonal Antibody

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.

Specifications

Antigen Phospho-Cofilin (Tyr140)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CFL1
Gene Accession No. P23528
Gene Alias 18 kDa phosphoprotein; AA959946; BOS_24828; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; COFILIN protein; Cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Tyr140.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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