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Phospho-CRK (Ser41) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986448
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100 μL
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50-198-6448 100 μL
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Catalog No. 50-198-6448 Supplier Bioss Supplier No. BS5264R
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Description

Rabbit Polyclonal Antibody

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Specifications

Antigen Phospho-CRK (Ser41)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Crk
Gene Accession No. P46108
Gene Alias Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; Crk; CRK proto-oncogene, adaptor protein; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CT-10 related kinase 3; p38; Proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian); v-crk sarcoma virus CT10 oncogene-like protein
Gene Symbols Crk
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human CRK around the phosphorylation site of Ser41 [DS (p-S)TS].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1398
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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