Invitrogen™ Phospho-Cyclin B3 (Thr257) Polyclonal Antibody

Catalog No.	Quantity
PIPA572377	400 μL

Catalog No. PIPA572377 Supplier Invitrogen™ Supplier No. PA572377

Description

Rabbit Polyclonal Antibody

Phospho-Cyclin B3 (Thr257) Polyclonal Antibody for DB

Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes. These complexes consist of a catalytic subunit associating with a specific regulatory subunit to form the active kinase. The cyclins, which include cyclin A, B, C, D, E, F, G, H, I, K, L, T and their related proteins, including Dbf4, comprise the regulatory subunits of these kinase complexes. The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit. Unlike the catalytic subunit, which is expressed continually, the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle, thereby regulating kinase activity. Cyclin B3, also known as CCNB3 or CYCB3, is a 1,395 amino acid nuclear protein that belongs to the cyclin family of regulatory proteins. Expressed in testis with lower expression in a variety of other tissues, cyclin B3 is thought to be required for early meiotic prophase I, playing an important role in the meiotic cell cycle. Three isoforms of cyclin B3 exist due to alternative splicing events.

Specifications

• Antigen: Phospho-Cyclin B3 (Thr257)
• Applications: Dot Blot
• Classification: Polyclonal
• Concentration: 0.7 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: CCNB3
• Gene Accession No.: Q810T2
• Gene Alias: CCNB3; CYCB3; cyclin B3; CyclinB3; G2/mitotic-specific cyclin-B3; Protein Ccnb3; RGD1564367
• Gene Symbols: CCNB3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T257 of mouse CCNB3.
• Purification Method: Antigen affinity chromatography, Protein A
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 209091
• Target Species: Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG