Phospho-Cyclin C (Ser275) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS14136R

Catalog No. 50-198-3204

Description

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.

Specifications

• Antigen: Phospho-Cyclin C (Ser275)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCNC
• Gene Alias: AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; Cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 892
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P24863
• Gene Symbols: CCNC
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Cyclin C around the phosphorylation site of Ser275.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG