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Phospho-DAXX (Ser517) Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS5292R

Encompass_Preferred

Catalog No. 50-198-6469


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Description

Description

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Specifications

Specifications

Phospho-DAXX (Ser517)
Polyclonal
Unconjugated
DAXX
BING2; BOS_21285; CENP-C binding protein; DADB-159G18.9; DAP6; DAXX; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246
Rabbit
Protein A
RUO
1616
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q9UER7
DAXX
KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser517.
100 μL
Primary
Human
Antibody
IgG
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