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Invitrogen™ Phospho-DEPDC5 (Thr1531) Polyclonal Antibody
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Catalog No. PIPA5106226
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100 μL
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PIPA5106226 100 μL
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Catalog No. PIPA5106226 Supplier Invitrogen™ Supplier No. PA5106226
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DEPDC5 only when phosphorylated at T1531.

This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DEPDC5 (Thr1531)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DEPDC5
Gene Accession No. O75140
Gene Alias DEP domain containing 5; DEP domain-containing protein 5; DEP.5; DEPD5; DEPDC5; FFEVF; GATOR complex protein DEPDC5; KIAA0645
Gene Symbols DEPDC5
Host Species Rabbit
Immunogen A synthesized peptide derived from human DEPDC5(Accession O75140), corresponding to amino acid residues around phosphorylated Ser1530.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9681
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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