Invitrogen™ Phospho-DEPDC6 (Ser244) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105064

Catalog No. PIPA5105064

Description

Antibody detects endogenous levels of DEPTOR only when phosphorylated at Ser244.

DEPDC6 is a gene that encodes a protein known for its role in various cellular processes, although the specifics of its function remain not fully elucidated. Located on chromosome 22, DEPDC6 is involved in regulating cell growth and survival by modulating the RAS signaling pathway, a crucial pathway for many cellular functions. Structurally, DEPDC6 contains a DEP domain, which is known to mediate interactions with other proteins that are involved in signal transduction. This domain plays a significant role in facilitating the proper localization and function of the protein. Functionally, DEPDC6 is implicated in controlling the pathways that govern the timing and progression of the cell cycle, highlighting its importance in maintaining cellular homeostasis and preventing uncontrolled cell proliferation. Its dysregulation has been associated with various cancers, emphasizing the need for further studies to fully understand its potential as a therapeutic target.

Specifications

• Antigen: Phospho-DEPDC6 (Ser244)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEPTOR
• Gene Alias: DEP domain containing 6; DEP domain containing MTOR interacting protein; DEP domain containing MTOR-interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEP.6; Depdc6; DEPTOR; Kiaa4200; RGD1561030
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 314979, 64798, 97998
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q570Y9, Q8TB45
• Gene Symbols: DEPTOR
• Immunogen: A synthesized peptide derived from human DEPTOR(Accession Q8TB45), corresponding to amino acid residues around phosphorylated Ser244.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov