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Invitrogen™ Phospho-DIAPH3 (Thr1061) Polyclonal Antibody
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Catalog No. PIPA5143678
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100 μL
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PIPA5143678 100 μL
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Catalog No. PIPA5143678 Supplier Invitrogen™ Supplier No. PA5143678
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Description

Rabbit Polyclonal Antibody

The antibody detects a 135 kDa* protein corresponding to mDia2 in immunoblots of human A7r5 and mouse C2C12 cells treated with calyculin A. The antibody detects transfected mDia2 after treatment with calyculin A, but this reactivity is removed after phosphatase treatment. In addition, the antibody does not detect mDia2 (T1061A) mutant.

This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DIAPH3 (Thr1061)
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene DIAPH3
Gene Accession No. Q9NSV4, Q9Z207
Gene Alias 4930417P13Rik; AN; AUNA1; DIA2; diap3; Diaph3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); diaphanous related formin 3; diaphanous-related formin; diaphanous-related formin 3; diaphanous-related formin-3; DKFZp434C0931; DKFZp686A13178; Drf3; FLJ34705; mDia2; mKIAA4117; NSDAN; p134MDia2; Protein diaphanous homolog 3
Gene Symbols DIAPH3
Host Species Rabbit
Immunogen Phospho-mDia2 (Thr-1061) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Thr-1061 in mouse mDia2 (Diap3). This peptide sequence is identical in rat and has 2 amino acid differences to human mDia2. The sequence has low homology to other formins.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290396, 56419, 81624
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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