Phospho-DNA-PK (Ser2056) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538478

Catalog No. PIPA538478

Description

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Specifications

• Antigen: Phospho-DNA-PK (Ser2056)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRKDC
• Gene Alias: DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19090, 5591
• Content And Storage: -20°C
• Form: Liquid

• Applications: Peptide ELISA
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P78527, P97313
• Gene Symbols: PRKDC
• Immunogen: A synthetic phosphopeptide derived from human DNA-PK around the phosphorylation site of Ser2056 (Y-S-SP-Q-D)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG